Jie Yu Selected Research

Enzymes

3/2024	Pyruvate kinase deficiency and PKLR gene mutations: Insights from molecular dynamics simulation analysis.
3/2024	Exosome-Inhibiting Polymeric Sonosensitizer for Tumor-Specific Sonodynamic Immunotherapy.
2/2024	M3 subtype of muscarinic acetylcholine receptor inhibits cardiac fibrosis via targeting microRNA-29b/beta-site app cleaving enzyme 1 axis.
3/2023	Protective effect and mechanism of Polygonatum kingianum against hypoxia-induced injury.
11/2022	Discovery of novel non-nucleoside inhibitors with high potency and selectivity for DNA methyltransferase 3A.
10/2022	Effects of a Novel Protease on Growth Performance, Nutrient Digestibility and Intestinal Health in Weaned Piglets.
1/2022	Netrin-1 induces the anti-apoptotic and pro-survival effects of B-ALL cells through the Unc5b-MAPK axis.
1/2021	Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors with Homozygous MTAP Deletion.
1/2021	m6A RNA hypermethylation-induced BACE2 boosts intracellular calcium release and accelerates tumorigenesis of ocular melanoma.
1/2019	Upregulation of CKIP-1 inhibits high-glucose induced inflammation and oxidative stress in HRECs and attenuates diabetic retinopathy by modulating Nrf2/ARE signaling pathway: an in vitro study.

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Jie Yu Research Topics

Disease

262	Neoplasms (Cancer) 05/2024 - 01/2002
83	Inflammation (Inflammations) 05/2024 - 07/2005
50	Infections 03/2024 - 05/2013
45	Hepatocellular Carcinoma (Hepatoma) 05/2024 - 12/2010
43	Neoplasm Metastasis (Metastasis) 05/2024 - 10/2005
40	Pain (Aches) 02/2024 - 09/2007
40	Body Weight (Weight, Body) 02/2024 - 04/2011
30	Necrosis 01/2023 - 05/2006
24	Type 2 Diabetes Mellitus (MODY) 04/2024 - 10/2007
23	Diarrhea 04/2024 - 05/2013
22	Fibrosis (Cirrhosis) 02/2024 - 02/2008
21	Breast Neoplasms (Breast Cancer) 05/2024 - 04/2005
20	Hypertension (High Blood Pressure) 04/2024 - 07/2012
20	Leukemia 12/2023 - 12/2009
19	Stroke (Strokes) 03/2024 - 08/2007
17	Carcinogenesis 12/2023 - 12/2003
17	Non-alcoholic Fatty Liver Disease 11/2023 - 01/2012
17	Hypoxia (Hypoxemia) 07/2023 - 09/2015
16	Wounds and Injuries (Trauma) 04/2024 - 07/2003
15	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2024 - 02/2015
14	Insulin Resistance 04/2024 - 10/2007
14	Neuralgia (Stump Neuralgia) 11/2022 - 06/2013
12	Hemorrhage 04/2024 - 11/2005
12	Heart Failure 03/2024 - 01/2021
12	Seizures (Absence Seizure) 11/2022 - 01/2012
11	Colorectal Neoplasms (Colorectal Cancer) 05/2024 - 01/2017
11	Myocardial Infarction 01/2024 - 01/2014
10	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 12/2023 - 01/2014
10	COVID-19 11/2023 - 01/2020
10	Cognitive Dysfunction 07/2023 - 01/2016
10	Liver Cirrhosis (Hepatic Cirrhosis) 04/2023 - 03/2012
9	Cardiovascular Diseases (Cardiovascular Disease) 05/2024 - 09/2014
9	Lung Neoplasms (Lung Cancer) 11/2023 - 05/2014
9	Mitochondrial Diseases (Mitochondrial Disease) 09/2023 - 01/2014
9	Endometriosis 01/2023 - 09/2007
9	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2023 - 07/2005
9	Rhabdomyosarcoma 01/2020 - 05/2006
8	Atherosclerosis 05/2024 - 01/2010
8	Colitis 01/2024 - 12/2017
8	Liver Neoplasms (Liver Cancer) 01/2024 - 12/2012
8	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 12/2023 - 09/2015
8	Birth Weight (Birth Weights) 12/2023 - 10/2012
8	Colonic Neoplasms (Colon Cancer) 05/2023 - 01/2014

Drug/Important Bio-Agent (IBA)

88	Proteins (Proteins, Gene)FDA Link 05/2024 - 11/2004
46	Messenger RNA (mRNA)IBA 02/2024 - 10/2005
39	Biomarkers (Surrogate Marker)IBA 05/2024 - 08/2010
38	CytokinesIBA 03/2024 - 11/2006
37	Glucose (Dextrose)FDA LinkGeneric 04/2024 - 01/2011
24	LipidsIBA 11/2023 - 05/2006
23	AntioxidantsIBA 04/2024 - 09/2007
20	DNA (Deoxyribonucleic Acid)IBA 05/2024 - 10/2003
19	EnzymesIBA 03/2024 - 04/2009
19	MicroRNAs (MicroRNA)IBA 02/2024 - 06/2014
19	RNA (Ribonucleic Acid)IBA 01/2024 - 01/2019
18	Therapeutic UsesIBA 01/2024 - 08/2007
17	Long Noncoding RNAIBA 01/2023 - 01/2017
15	SaltsIBA 03/2024 - 02/2010
15	SodiumIBA 02/2024 - 12/2017
15	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2023 - 06/2012
14	Interleukin-6 (Interleukin 6)IBA 12/2022 - 07/2008
13	Insulin (Novolin)FDA Link 04/2023 - 07/2006
12	Triglycerides (Triacylglycerol)IBA 04/2024 - 09/2014
12	Doxorubicin (Adriamycin)FDA LinkGeneric 04/2022 - 04/2012
11	Antiviral Agents (Antivirals)IBA 03/2024 - 10/2010
11	Anti-Bacterial Agents (Antibiotics)IBA 12/2023 - 11/2011
11	AlbuminsIBA 08/2023 - 09/2014
10	nonylphenolIBA 02/2024 - 01/2017
10	Polysaccharides (Glycans)IBA 02/2024 - 10/2010
10	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2023 - 01/2015
10	Small Interfering RNA (siRNA)IBA 04/2023 - 01/2015
10	Hemoglobins (Hemoglobin)IBA 03/2023 - 12/2013
10	Blood Glucose (Blood Sugar)IBA 01/2023 - 01/2012
10	Analgesics (Analgesic Drugs)IBA 01/2023 - 02/2014
9	CollagenIBA 02/2024 - 02/2008
9	Hormones (Hormone)IBA 07/2023 - 10/2005
9	Oxygen (Dioxygen)IBA 01/2023 - 03/2008
9	NitrogenIBA 04/2022 - 03/2014
8	PotassiumIBA 03/2024 - 06/2019
8	Endocrine DisruptorsIBA 02/2024 - 01/2017
8	C-Reactive ProteinIBA 02/2024 - 10/2007
8	salicylhydroxamic acid (SHAM)IBA 01/2024 - 05/2006
8	CalciumIBA 10/2023 - 01/2017
8	Fluorouracil (Carac)FDA LinkGeneric 05/2023 - 05/2015
8	Amino Acids FDA Link 01/2023 - 04/2005
8	Contrast MediaIBA 01/2023 - 05/2006
8	1-phenyl-3,3-dimethyltriazene (PDT)IBA 01/2023 - 01/2008

Therapy/Procedure

166	Therapeutics 04/2024 - 01/2002
61	Drug Therapy (Chemotherapy) 02/2024 - 08/2008
26	Immunotherapy 05/2024 - 04/2011
13	Aftercare (After-Treatment) 06/2023 - 03/2009
12	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2024 - 01/2014
12	Radiotherapy 11/2023 - 01/2012
11	Lasers (Laser) 01/2024 - 11/2007
11	Photothermal Therapy 01/2022 - 02/2010
10	Transplantation 01/2024 - 07/2003
10	Precision Medicine 11/2023 - 01/2012
9	Photochemotherapy (Photodynamic Therapy) 01/2023 - 01/2008
9	Ligation 08/2022 - 11/2005
8	Hematopoietic Stem Cell Transplantation 05/2024 - 03/2009
8	Length of Stay 02/2024 - 12/2012